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Department Name:

Metabolic Regulation

H.O.D Name:

Dr. Chinmay Kumar Panda, M.Sc, Ph.D

Contact:

Email: chinmaykumar.panda@cnci.org.in
Phone No:91-33-2476-5101 (ext-328)
Fax No:91-33-475-7606

Objective:

As a continuation of the work done in the previous year the therapeutic effect of anti-ganglioside antibody raised against Ehrlich’s Ascites Carcinoma (EAC) cell gangliosides in rat was studied on the same tumor in vivo in relation to angiogenesis. Expression of vascular endothelial factor (VEGF), a vital factor which regulates and promotes tumor angiogenesis has been studied in the EAC cells in relation to angiogenesis of EAC tumor after anti-ganglioside antibody treatment. Secretion of the same factor in the blood circulation and ascites fluid of EAC-ascites tumor bearing mice after anti-ganglioside antibody treatment has also been studied. A definite correlation has been observed between therapeutic effect of anti-ganglioside antibody and VEGF level in relation to angiogenesis.

Lab Member:

HOD: Dr. Chinmay Kumar Panda, M.Sc, Ph.D.
Dr. Sarmistha Das Banerjee,M.Sc, Ph.D, Senior Scientific Officer, GrII.
Dr. Joyati Mukherjee Basu,M.Sc, Ph.D, Senior Scientific Officer, GrII.
Ms. Bipasa Mandal,M.Sc, Sr. Research Fellow.

Brief description of the ongoing research work:

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